Author

T -C Liu

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 4

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 4 Organism:human· 4 Approach:statistical model· 4 Research Focus:database / resource· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:long-read sequencing· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Daofeng LiiD· 3 shared Edward A. BelteriD· 3 shared Juan F. Macias-VelascoiD· 3 shared Ting WangiD· 3 shared Wenjin ZhangiD· 3 shared Zheng DongiD· 3 shared Benpeng MiaoiD· 2 shared Chad TomlinsoniD· 2 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersGenomics

Daofeng LiORCID

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4 papers

Recent·Most cited

Human panepigenome represents epigenomic diversity

Zheng Dong, Juan F. Macias-Velasco, Xiaoyu Zhuo, Wenjin Zhang, Chad Tomlinson, Juan Jiang, Edward A. Belter, Saifur Rahman Jony, Ronghan Li, Robert S. Fulton, Shihua Dong, T -C Liu, Daofeng Li, Ting Wang

The paper presents a human panepigenome map of DNA methylation, revealing epigenomic diversity across populations and highlighting the role of genetic variation in CpG presence and absence.

bioRxiv · Aug 23, 2026 · PreprintGenomics

HPRC2: A human pangenome reference with near-complete coverage of common genetic variation

Julian Lucas, Prajna Hebbar, Wen‐Wei Liao, Juan F Macias-Velasco, Adam M. Novak, Mobin Asri, Jennifer Balacco, Andrew P. Blair, Jana Ebler, Joshua M.V. Gardner, Margarita Geleta, Cristian Groza, Andrea Guarracino, Peter Heringer, Glenn Hickey, , Jane E. Loveland

460 haplotypes from 230 genomes, selected to maximize common-variant coverage, capture 99.43% of All of Us common small variants and halve structurally unreliable regions and base errors versus HPRC1.

bioRxiv · Jul 22, 2026 · PreprintGenomics✦ In-depth digest

Fully T2T pedigree assemblies reveal genetic stability and epigenetic plasticity of human centromeres across inheritance and cell-fate transitions

Shihua Dong, Xiaoyun Xing, Monika Čechová, Hailey Loucks, Selvamani Vijayalingam, Amber Neilson, Monica F. Sentmanat, Juan F. Macias-Velasco, T -C Liu, Zheng Dong, Benpeng Miao, Wenjin Zhang, Chad Tomlinson, Heather K. Schmidt, Edward A. Belter, , Ting Wang

The paper uses fully phased telomere-to-telomere assemblies and long-read epigenomes to study centromere genetic and epigenetic dynamics across inheritance and cell-fate transitions, finding positional stability of CDRs and dynamic epigenetic changes.

bioRxiv · Feb 17, 2026 · PreprintGenomics

An Integrated Single-Cell and Epigenomic Resource for Comparative Analysis of the Basal Ganglia

Wenjin Zhang, Wubin Ding, Kai Li, Lei Chang, Amit Klein, Cindy Tatiana Báez-Becerra, Jonathan A. Rink, Anna Bartlett, Huaming Chen, Natalie M. Schenker-Ahmed, Nelson Johansen, Tyler S. Mollenkopf, Yuanyuan Fu, Xie Yang, Shane Liu, , Daofeng Li

The paper presents an integrated single-cell and epigenomic resource for exploring basal ganglia datasets across species, enabling multi-omics and comparative analysis.

bioRxiv · Feb 2, 2026 · PreprintGenomics