Xiaoyun Xing

The paper investigates sex-specific molecular responses to early-life toxicant exposures in mice across multiple life stages using transcriptomic and epigenomic data.

The paper uses fully phased telomere-to-telomere assemblies and long-read epigenomes to study centromere genetic and epigenetic dynamics across inheritance and cell-fate transitions, finding positional stability of CDRs and dynamic epigenetic changes.

The paper characterizes persistent epigenomic and transcriptomic changes in mice exposed to environmental toxicants across life stages, revealing widespread gene expression and chromatin alterations.

This study examines transcriptomic and epigenetic changes in four rat brain regions after a METH overdose, revealing region-specific responses and conserved regulatory elements linked to neurological functions.

This study quantifies how transposable elements contribute to 3D genome structure and gene regulation across species and cell types, showing their role in shaping chromatin organization and gene expression.

This study demonstrates the feasibility of creating multi-dimensional genomic maps for juvenile idiopathic arthritis using limited patient samples and identifies epigenetic and genetic features associated with the disease.