Inhibiting ezrin triggers formin-mediated actin remodelling reducing cellular mechano-protection
Ananya Biswas, Rinku Kumar, T N Husain, Jibitesh Das, Amrutamaya Behera, Bidisha Sinha
This study shows that inhibiting ezrin reduces mechano-protection in cells by altering actin organization and increasing stress fibre formation, which is mitigated by formin inhibition.
bioRxiv · Jul 22, 2025 · PreprintBiophysics