Using polyacrylamide hydrogels to model physiological aortic stiffness reveals that microtubules are critical regulators of isolated smooth muscle cell morphology and contractility.
S. Ahmed, R. T. Johnson, R. Solanki, T. Afewerki, F. Wostear, D. T. Warren
This study uses polyacrylamide hydrogels to model aortic stiffness and shows microtubules regulate VSMC morphology and contractility by balancing actomyosin forces.
bioRxiv · Dec 14, 2021Cell Biology