R. T. Johnson

A microtubule stability switch alters isolated vascular smooth muscle calcium flux in response to matrix rigidity

The paper shows that microtubule stability regulates vascular smooth muscle cell volume and calcium flux in response to matrix rigidity.

Endothelial neuropilin-1 and neuropilin-2 are essential for tumour angiogenesis

This study shows that targeting both endothelial neuropilin-1 and neuropilin-2 inhibits tumour angiogenesis and metastasis in mouse models.

Simulated hemiparesis increases optimal spatiotemporal gait asymmetry but not metabolic cost

This study uses predictive musculoskeletal modeling to show that unilateral muscle weakness increases spatiotemporal gait asymmetry but not metabolic cost in post-stroke models.

Using polyacrylamide hydrogels to model physiological aortic stiffness reveals that microtubules are critical regulators of isolated smooth muscle cell morphology and contractility.

This study uses polyacrylamide hydrogels to model aortic stiffness and shows microtubules regulate VSMC morphology and contractility by balancing actomyosin forces.

The Effects of Posture on the Three-Dimensional Gait Mechanics of Human Walking in Comparison to Bipedal Chimpanzees

This study compares human crouched posture gait mechanics with bipedal chimpanzee gait, finding similarities and differences in kinematics and ground reaction forces.

Using Bayesian Inference to Estimate Plausible Muscle Forces in Musculoskeletal Models

This paper uses Bayesian inference to estimate muscle forces in musculoskeletal models, finding plausible force ranges while accounting for uncertainty, though convergence issues remain.

The β3-integrin endothelial adhesome regulates microtubule dependent cell migration

This study shows that β3-integrin regulates microtubule stability in endothelial cells through Rcc2/Anxa2 and Rac1, affecting cell migration and angiogenesis.