VRK3 depletion induces cell cycle arrest and metabolic reprogramming of Pontine Diffuse Midline Glioma (DMG)-K27 altered cells
V. Menez, T. Kergrohen, T. Sasha, C. Silva-Evangelista, L. Ledret, L. Auffret, C. Subecz, M. Lancien, Y. Ajlil, K. Beccaria, T. Blauwblomme, E. Oberlin, J. Grill, D. Castel, M.-A. Debily
This study shows VRK3 depletion causes cell cycle arrest and metabolic reprogramming in DMG-K27M cells, with potential therapeutic implications.
bioRxiv · Mar 24, 2023 · PreprintCancer Biology