Author

T. Brusko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

A. L. Posgai· 2 shared L. Sachs· 2 shared M. Brown· 2 shared M. Brusko· 2 shared M. Shapiro· 2 shared P. Thirawatananond· 2 shared A. Posgai· 1 shared C. E. Mathews· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

A. L. Posgai

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Author profile →

3 papers

Recent·Most cited

Inhibition of CD226 Co-Stimulation Suppresses Diabetes Development in the NOD Mouse by Augmenting Tregs and Diminishing Effector T Cell Function

M. Brown, P. Thirawatananond, L. Peters, E. Kern, S. Vijay, L. Sachs, A. L. Posgai, M. Brusko, M. Shapiro, C. E. Mathews, R. E. Bacher, T. Brusko

This study shows that blocking CD226 reduces diabetes in NOD mice by enhancing Treg function and reducing effector T cell activity.

bioRxiv · Jul 16, 2024 · PreprintImmunology

Deletion of CD226 in Foxp3+ T cells Reduces Diabetes Incidence in Non-Obese Diabetic Mice by Improving Regulatory T Cell Stability and Function

P. Thirawatananond, M. Brown, L. Sachs, J. Arnoletti, W.-I. Yeh, A. L. Posgai, M. Shapiro, Y.-G. Chen, T. Brusko

This study shows that deleting CD226 in regulatory T cells reduces diabetes in NOD mice by enhancing Treg stability and function.

bioRxiv · Jun 2, 2022 · PreprintImmunology

Immune, endothelial and neuronal network map in human lymph node and spleen

S. Currlin, H. Nick, M. Jorgensen, J. Nick, M. Brusko, H. Hakimian, J. Penaloza-Aponte, N. Rodriguez, M. Medina-Serpas, M. Yang, R. Seifert, I. Kusmartseva, T. Brusko, K. Otto, A. Posgai, , M. A. Atkinson

The paper maps immune, endothelial, and neuronal networks in human spleen and lymph node using multiplex imaging, revealing novel cellular localization patterns.

bioRxiv · Oct 20, 2021 · PreprintImmunology