Author

T. C. Cornish

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:deep learning· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. L. Kiemen· 3 shared A. M. Braxton· 3 shared D. Wirtz· 3 shared L. D. Wood· 3 shared R. H. Hruban· 3 shared E. D. Thompson· 2 shared M. P. Grahn· 2 shared P.-H. Wu· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

A. L. Kiemen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Power-law growth models explain incidences and sizes of pancreatic cancer precursor lesions and confirm spatial genomic findings

A. L. Kiemen, P. Wu, A. M. Braxton, T. C. Cornish, R. H. Hruban, L. D. Wood, D. Wirtz, D. Zwicker

The paper uses AI-based 3D tissue mapping to show PanIN lesion sizes follow a power-law distribution and identifies growth mechanisms driving pancreatic cancer precursor lesions.

bioRxiv · Dec 1, 2023Biophysics

Three-dimensional genomic mapping of human pancreatic tissue reveals striking multifocality and genetic heterogeneity in precancerous lesions

A. M. Braxton, A. L. Kiemen, M. P. Grahn, A. Forjaz, J. M. Babu, L. Zheng, L. Jiang, H. Cheng, Q. Song, R. Reichel, S. Graham, A. I. Damanakis, C. G. Fischer, S. Mou, C. Metz, , L. D. Wood

This study uses 3D imaging and genomic analysis to show that human pancreatic precancerous lesions (PanINs) are highly multifocal and genetically heterogeneous.

bioRxiv · Jan 27, 2023 · PreprintCancer Biology

In situ characterization of the 3D microanatomy of the pancreas and pancreatic cancer at single cell resolution

A. L. Kiemen, A. M. Braxton, M. P. Grahn, K. S. Han, J. Mahesh Babu, R. Reichel, F. Amoa, S.-M. Hong, T. C. Cornish, E. D. Thompson, L. D. Wood, R. H. Hruban, P.-H. Wu, D. Wirtz

The paper develops a method to reconstruct 3D pancreatic tissue at single-cell resolution and maps cancer invasion modes in the tumor microenvironment.

bioRxiv · Dec 8, 2020Cancer Biology