Author

C. Metz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

F. Campagne· 2 shared H. Zhao· 2 shared L. Blanc· 2 shared P. Chandakkar· 2 shared P. Chatterjee· 2 shared P. Marambaud· 2 shared S. Ruiz· 2 shared A. Becker· 1 shared

Activity by Year

2016-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCell Biology

F. Campagne

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Three-dimensional genomic mapping of human pancreatic tissue reveals striking multifocality and genetic heterogeneity in precancerous lesions

A. M. Braxton, A. L. Kiemen, M. P. Grahn, A. Forjaz, J. M. Babu, L. Zheng, L. Jiang, H. Cheng, Q. Song, R. Reichel, S. Graham, A. I. Damanakis, C. G. Fischer, S. Mou, C. Metz, , L. D. Wood

This study uses 3D imaging and genomic analysis to show that human pancreatic precancerous lesions (PanINs) are highly multifocal and genetically heterogeneous.

bioRxiv · Jan 27, 2023 · PreprintCancer Biology

Autoantibodies against Progranulin and IL-1 receptor antagonist due to immunogenic posttranslational isoforms contribute to hyperinflammation in critically ill COVID-19

L. Thurner, N. Fadle, M. Bewarder, I. Kos, E. Regitz, O. Cetin, B. Thurner, Y. Fischer, T. Rixecker, K.-D. Preuss, C. Schormann, F. Neumann, S. Hartmann, T. Bock, D. Kaddu-Mulindwa, , S. Koerper

This study identifies autoantibodies against PGRN and IL-1-Ra in critical COVID-19 patients, linked to hyperphosphorylated isoforms and increased inflammation.

bioRxiv · Apr 23, 2021 · PreprintImmunology

Sirolimus plus nintedanib treats vascular pathology in HHT mouse models

S. Ruiz, H. Zhao, P. Chandakkar, J. Papoin, H. Choi, A. Nomura-Kitabayashi, R. Patel, M. Gillen, L. Diao, P. Chatterjee, M. He, Y. Al-Abed, P. Wang, C. Metz, S. P. Oh, , P. Marambaud

This study shows that combining sirolimus and nintedanib treats vascular abnormalities in HHT mouse models by targeting multiple pathways.

bioRxiv · Aug 18, 2019 · PreprintCell Biology

A mouse model of hereditary hemorrhagic telangiectasia generated by transmammary-delivered immunoblocking of BMP9 and BMP10

S. Ruiz, H. Zhao, P. Chandakkar, P. Chatterjee, L. Blanc, C. Metz, F. Campagne, P. Marambaud

This study uses transmammary delivery of anti-BMP9/10 antibodies to induce HHT-like vascular defects in mouse neonates, revealing consistent retinal pathology and increased angiopoietin-2 expression.

bioRxiv · Nov 2, 2016Cell Biology