Author

T. D. Nilaweera

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

D. A. Nyenhuis· 2 shared D. S. Cafiso· 2 shared R. Nakamoto· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersBiophysics

D. A. Nyenhuis

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2 papers

Recent·Most cited

Structural intermediates observed only in intact Escherichia coli indicate a mechanism for TonB-dependent transport

T. D. Nilaweera, D. A. Nyenhuis, D. S. Cafiso

The paper uses pulse EPR to study BtuB in intact E. coli, showing substrate binding induces structural changes regulated by TonB, not observed in reconstituted systems.

bioRxiv · Mar 18, 2021Biophysics

Disulfide chaperone knock-outs enable in-vivo double spin-labeling of an outer-membrane transporter

D. S. Cafiso, T. D. Nilaweera, D. A. Nyenhuis, R. Nakamoto

The paper shows that disulfide bond formation in E. coli prevents double spin-labeling of BtuB cysteines, but dsbA/B null mutants enable this labeling and reveal structural differences in vivo.

bioRxiv · Jul 22, 2019Biophysics