Engineering Alignment has Mixed Effects on hiPSC-CM Maturation
N. Kalkunte, T. Delambre, S. Sohn, M. Pickett, S. H. Parekh, J. Zoldan
This paper shows engineered alignment improves hiPSC-CM maturity by affecting electrochemical coupling and mitochondrial morphology, but also notes metabolic shifts during differentiation.
bioRxiv · Sep 26, 2022Bioengineering