Author

J. Zoldan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 8

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:cell type annotation· 5 Organism:human· 5 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

N. Kalkunte· 3 shared S. H. Parekh· 3 shared B. Harley· 2 shared C. Crosby· 2 shared S. Kumar· 2 shared S. Sohn· 2 shared T. Delambre· 2 shared A. Brock· 1 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersBioengineering

N. Kalkunte

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Dynamic Electrical Stimulation Promotes hiPSC-CM Differentiation and Functionality

N. Kalkunte, S. Sohn, T. Delambre, S. Meng, A. Brock, J. Zoldan

This study shows that dynamic electrical stimulation improves hiPSC-CM differentiation, functionality, and transcriptomic pathway enrichment compared to static or no stimulation.

bioRxiv · May 1, 2024 · PreprintBioengineering

Endometrial decidualization status modulates endometrial perivascular complexity and trophoblast outgrowth in gelatin hydrogels

S. G. Zambuto, H. Theriault, I. Jain, C. Crosby, I. Pintescu, N. Y. Chiou, J. Zoldan, G. Underhill, K. B. Clancy, B. Harley

This study creates an artificial endometrial perivascular niche in hydrogels to study how decidualization affects vessel complexity and trophoblast outgrowth.

bioRxiv · Nov 8, 2022 · PreprintBioengineering

SARS-CoV-2 spike protein induces endothelial dysfunction in 3D engineered vascular networks

B. Stern, P. Monteleone, J. Zoldan

This study uses a 3D in vitro model to show that SARS-CoV-2 spike protein causes endothelial dysfunction, which can be mitigated by dexamethasone.

bioRxiv · Oct 1, 2022Bioengineering

Engineering Alignment has Mixed Effects on hiPSC-CM Maturation

N. Kalkunte, T. Delambre, S. Sohn, M. Pickett, S. H. Parekh, J. Zoldan

This paper shows engineered alignment improves hiPSC-CM maturity by affecting electrochemical coupling and mitochondrial morphology, but also notes metabolic shifts during differentiation.

bioRxiv · Sep 26, 2022Bioengineering

Biomechanical dependence of SARS-CoV-2 infections

A. Paul, S. Kumar, T. Kaoud, M. R. Pickett, A. L. Bohanon, J. Zoldan, K. N. Dalby, S. H. Parekh

This study investigates how lung biomechanical changes with age affect SARS-CoV-2 infection rates using hydrogels and fiber matrices, finding higher infection rates on softer scaffolds resembling younger lungs.

bioRxiv · Feb 17, 2022Bioengineering

Towards prevention of re-entrant arrhythmias: Injectable hydrogel electrodes enable direct capture of previously inaccessible cardiac tissues

G. Rodriguez-Rivera, A. Post, M. John, S. Buchan, M. Wancura, M. Chwatko, C. Waldron, A. Nkansah, D. Bernard, N. Kalkunte, J. Zoldan, M. Arseneault, M. Razavi, E. Cosgriff-Hernandez

This paper develops injectable hydrogel electrodes that can pace previously inaccessible mid-myocardial tissue, mimicking physiologic conduction and offering a potential alternative to current arrhythmia treatments.

bioRxiv · Nov 3, 2021 · PreprintBioengineering

Quantification of iPSC-derived vascular networks in novel phototunable angiogenic hydrogels

C. O. Crosby, A. Hillsley, S. Kumar, S. H. Parekh, A. Rosales, J. Zoldan

This paper develops a tunable hydrogel for iPSC-derived vascular network formation and shows that stiffness modulation affects vascular growth.

bioRxiv · Aug 25, 2020 · PreprintBioengineering

Perivascular Secretome Influences Hematopoietic Stem Cell Maintenance in a Gelatin Hydrogel

V. R. Barnhouse, N. Petrikas, C. Crosby, J. Zoldan, B. Harley

This study develops a 3D gelatin hydrogel model of the perivascular niche to show that its secretome promotes HSC maintenance in vitro.

bioRxiv · Apr 25, 2020Bioengineering