Hepatic WDR23 proteostasis mediates insulin clearance by regulating insulin degrading enzyme activity
C. Duangjan, T. E. Arpawong, B. N. Spatola, S. P. Curran
This study shows that WDR23 proteostasis regulates insulin-degrading enzyme activity in the liver, affecting insulin clearance and metabolic health.
bioRxiv · Nov 24, 2022 · PreprintCell Biology