Novel keto-alkyl-pyridinium antifungal molecules active in models of in vivo Candida albicans vascular catheter infection and ex vivo Candida auris skin colonization
S. R. Beattie, T. Esan, R. Zaronowaki, E. Eix, J. E. Nett, D. R. Andes, T. Hagen, D. J. Krysan
This study identifies and characterizes novel keto-alkyl-pyridinium antifungal molecules with broad spectrum activity against fungi, showing efficacy in in vivo and ex vivo models of infection.
bioRxiv · Jan 19, 2023 · PreprintMicrobiology