Author

T. Hollis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Kumbhar· 1 shared B.-O. Davids· 1 shared C. Dash· 1 shared F. R. Salsbury· 1 shared F. W. Perrino· 1 shared J. Davis· 1 shared J. Pandhare· 1 shared M. Balasubramaniam· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

B. Kumbhar

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Author profile →

2 papers

Recent·Most cited

Three Prime Repair Exonuclease 1 preferentially degrades the integration-incompetent HIV-1 DNA through favorable kinetics, thermodynamic, structural and conformational properties.

P. Prakash, P. Khodke, M. Balasubramaniam, B.-O. Davids, T. Hollis, J. Davis, J. Pandhare, B. Kumbhar, C. Dash

This study identifies how TREX1 preferentially degrades unprocessed HIV-1 DNA over 3-processed DNA through kinetic, thermodynamic, and structural differences.

bioRxiv · Mar 19, 2024Biochemistry

A TREX1 model reveals double-strand DNA preference and inter-protomer regulation

W. O. Hemphill, T. Hollis, F. R. Salsbury, F. W. Perrino

This study investigates TREX1 exonuclease activity, revealing its preference for double-strand DNA and inter-protomer regulation through biochemical assays, simulations, and modeling.

bioRxiv · Feb 25, 2022 · PreprintBiochemistry