Author

B.-O. Davids

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Dash· 2 shared J. Pandhare· 2 shared M. Balasubramaniam· 2 shared A. Bryer· 1 shared B. Kumbhar· 1 shared C. Aiken· 1 shared C. Xu· 1 shared J. Davis· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiochemistry

C. Dash

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2 papers

Recent·Most cited

Three Prime Repair Exonuclease 1 preferentially degrades the integration-incompetent HIV-1 DNA through favorable kinetics, thermodynamic, structural and conformational properties.

P. Prakash, P. Khodke, M. Balasubramaniam, B.-O. Davids, T. Hollis, J. Davis, J. Pandhare, B. Kumbhar, C. Dash

This study identifies how TREX1 preferentially degrades unprocessed HIV-1 DNA over 3-processed DNA through kinetic, thermodynamic, and structural differences.

bioRxiv · Mar 19, 2024Biochemistry

HIV-1 Mutants that Escape the Cytotoxic T-Lymphocytes are Defective in Viral DNA Integration

M. Balasubramaniam, S. Thapa, B.-O. Davids, A. Bryer, C. Xu, J. Shi, C. Aiken, J. Pandhare, J. R. Perilla, C. Dash

This study shows that an HIV-1 mutation escaping CTL response impairs viral DNA integration, and compensatory mutations or host factors can rescue this defect.

bioRxiv · Aug 29, 2021Microbiology