Branched chain amino acid aminotransferase 2 Regulates Ferroptotic Cell Death in Cancer Cells
K. Wang, Z. Zhang, T. Hsiang-i, Y. Liu, M. Wang, L. Song, X. Cao, Z. Xu, H. Chen, A. Gong, D. Wang, F. Cheng, H. Zhu
This study identifies BCAT2 as a suppressor of ferroptosis in cancer cells, showing its role in regulating glutamate levels and enhancing resistance to ferroptosis-inducing therapies.
bioRxiv · Feb 17, 2020Cancer Biology