SLX4IP-mediated telomere maintenance is essential for androgen receptor-independent castration-resistant prostate cancer
T. L. Mangosh, W. N. Awadallah, M. M. Grabowska, D. J. Taylor
This study shows that SLX4IP-mediated ALT is critical for AR-independent CRPC survival, as its inhibition leads to telomere shortening and senescence.
bioRxiv · Mar 31, 2020Cancer Biology