M. M. Grabowska

IL1B loss is associated with increased AR activity in castration-resistant prostate cancer

This study shows that loss of IL1B increases AR activity in castration-resistant prostate cancer cells, even without androgens.

Microbial metabolites of flavanols in urine are associated with enhanced anti-proliferative activity in bladder cancer cells in vitro

The paper investigates the anti-proliferative effects of flavanol microbial metabolites in urine on bladder cancer cells and finds that these metabolites are more strongly associated with reduced cell proliferation than native flavanols.

Increased nuclear factor I/B expression in prostate cancer correlates with AR expression

The paper examines NFIB expression in prostate cancer, showing its correlation with AR and its nuclear/cytoplasmic localization, and demonstrates an AR-NFIB interaction.

SLX4IP-mediated telomere maintenance is essential for androgen receptor-independent castration-resistant prostate cancer

This study shows that SLX4IP-mediated ALT is critical for AR-independent CRPC survival, as its inhibition leads to telomere shortening and senescence.

Identification of genes required for enzalutamide resistance in castration-resistant prostate cancer cells in vitro

This study identifies three genes (ACAT1, MAP3K11, and PSMD12) that support enzalutamide resistance in castration-resistant prostate cancer cells in vitro.

Prostatic osteopontin expression is associated with symptomatic benign prostatic hyperplasia

This study shows that osteopontin (OPN) is more abundant in symptomatic benign prostatic hyperplasia (S-BPH) compared to incidental BPH, and OPN secretion is stimulated by pro-inflammatory cytokines, driving pro-inflammatory gene expression in stromal cells.