Limited SARS-CoV-2 diversity within hosts and following passage in cell culture
G. K. Moreno, K. M. Braun, P. J. Halfmann, T. M. Prall, K. K. Riemersma, A. K. Haj, J. Lalli, K. R. Florek, T. C. Friedrich, Y. Kawaoka, D. H. O'Connor
This study analyzes SARS-CoV-2 within-host diversity using metagenomic sequencing and finds low genetic variation with limited evidence of positive selection in clinical and cell culture samples.
bioRxiv · Apr 20, 2020 · PreprintMicrobiology