Author

G. K. Moreno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:variant calling· 3 Approach:experimental assay· 2 Organism:human· 2 Organism:rat· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

A. K. Haj· 3 shared D. A. Baker· 3 shared D. H. O'Connor· 3 shared A. M. Weiler· 2 shared D. M. Dudley· 2 shared D. O'Connor· 2 shared K. Koelle· 2 shared K. M. Braun· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

A. K. Haj

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Limited within-host diversity and tight transmission bottlenecks limit SARS-CoV-2 evolution in acutely infected individuals

K. Braun, G. K. Moreno, C. Wagner, M. A. Accola, W. M. Rehrauer, D. A. Baker, K. Koelle, D. O'Connor, T. Bedford, T. Friedrich, L. H. Moncla

The paper analyzes SARS-CoV-2 within-host diversity and transmission bottlenecks in acute infections, finding limited diversity and narrow bottlenecks that restrict variant spread.

bioRxiv · Apr 30, 2021 · PreprintEvolutionary Biology

Transmission of SARS-CoV-2 in domestic cats imposes a narrow bottleneck

K. M. Braun, G. K. Moreno, P. J. Halfmann, E. B. Hodcroft, D. A. Baker, E. C. Boehm, A. M. Weiler, A. K. Haj, M. Hatta, S. Chiba, T. Maemura, Y. Kawaoka, K. Koelle, D. O'Connor, T. Friedrich

This study shows SARS-CoV-2 in cats has limited within-host genetic variation and a narrow transmission bottleneck, with a variant H655Y emerging and spreading across transmission pairs.

bioRxiv · Nov 16, 2020Microbiology

Limited SARS-CoV-2 diversity within hosts and following passage in cell culture

G. K. Moreno, K. M. Braun, P. J. Halfmann, T. M. Prall, K. K. Riemersma, A. K. Haj, J. Lalli, K. R. Florek, T. C. Friedrich, Y. Kawaoka, D. H. O'Connor

This study analyzes SARS-CoV-2 within-host diversity using metagenomic sequencing and finds low genetic variation with limited evidence of positive selection in clinical and cell culture samples.

bioRxiv · Apr 20, 2020 · PreprintMicrobiology

High-throughput identification of MHC class I binding peptides using an ultradense peptide array

A. K. Haj, M. E. Breitbach, D. A. Baker, M. S. Mohns, G. K. Moreno, N. A. Wilson, V. Lyamichev, J. Patel, K. L. Weisgrau, D. M. Dudley, D. H. O'Connor

This paper uses an ultradense peptide array to identify MHC class I binding peptides, finding 64% of known epitopes and three novel ones in rhesus macaques.

bioRxiv · Jul 31, 2019Immunology

Long-term protection of rhesus macaques from Zika virus reinfection

G. K. Moreno, C. M. Newman, M. R. Koenig, M. S. Mohns, A. M. Weiler, S. L. Rybarczyk, L. J. Vosler, N. L. Pomplun, N. Schultz-Darken, E. Rakasz, D. M. Dudley, T. C. Friedrich, D. H. O'Connor

This study shows that rhesus macaques retain neutralizing antibodies against ZIKV for at least 27 months, protecting them from detectable plasma viremia upon rechallenge.

bioRxiv · Jul 23, 2019Immunology