Murine norovirus capsid plasticity - Glycochenodeoxycholic acid stabilizes P domain dimers and triggers escape from antibody recognition
R. Creutznacher, T. Maass, J. Duelfer, C. Feldmann, V. Hartmann, J. Knickmann, L. T. Westermann, T. J. Smith, C. Uetrecht, A. Mallagaray, T. Peters, S. Taube
This paper investigates how GCDCA stabilizes MNV P-domain dimers, leading to structural changes that enable immune escape by preventing antibody recognition.
bioRxiv · Feb 27, 2021Biochemistry