Author

T. Maehigashi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

C. M. Dunham· 2 shared E. D. Hoffer· 2 shared C. E. Fagan· 1 shared H. A. Nguyen· 1 shared P. Whitford· 1 shared R. L. Gonzalez· 1 shared S. Hong· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

C. M. Dunham

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2 papers

Recent·Most cited

Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches

H. A. Nguyen, C. E. Fagan, E. D. Hoffer, T. Maehigashi, C. M. Dunham

The paper presents crystal structures showing how a P-site codon-anticodon mismatch reduces A-site fidelity, allowing for quality control of protein synthesis.

bioRxiv · Jan 28, 2023Biochemistry

Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing

E. D. Hoffer, S. Hong, T. Maehigashi, R. L. Gonzalez, P. Whitford, C. M. Dunham

The paper reports ribosome structures with tRNAPro bound to codons, showing how m1G37 modification prevents frameshifting by stabilizing tRNA interactions.

bioRxiv · Sep 1, 2020Biochemistry