Thioredoxin reductase controls the capacity of peroxiredoxins to limit mitochondrial H2O2 release
M. N. Hoehne, L. J. Jacobs, K. J. Lapacz, L. M. Murschall, T. Marker, B. Morgan, M. Fricker, V. Belousov, J. Riemer
The paper investigates mitochondrial H2O2 release in mammalian cells and finds that peroxiredoxins 1 and 2 control H2O2 gradients and handling through dynamic adaptation of thioredoxin reductase.
bioRxiv · Jul 8, 2021 · PreprintBiochemistry