Autophagy cargo receptors are secreted via extracellular vesicles and particles in response to endolysosomal inhibition or impaired autophagosome maturation
T. A. Solvik, T. A. Nguyen, Y.-H. T. Lin, T. Marsh, E. J. Huang, A. P. Wiita, J. Debnath, A. M. Leidal
This study identifies a secretory autophagy pathway that releases autophagy cargo receptors via extracellular vesicles when endolysosomal function is inhibited or autophagosome maturation is disrupted.
bioRxiv · Aug 12, 2021Cell Biology