T. N. McNeilly

Tuft cell-derived acetylcholine is an effector of type 2 immunity and directly targets helminth parasites in the gut lumen

The paper shows tuft cells release acetylcholine to directly target helminth parasites in the gut, enhancing type 2 immunity.

Characterisation of protective vaccine antigens from the thiol-containing components of excretory/secretory material of Ostertagia ostertagi

The paper identifies and characterizes protective antigens in a vaccine preparation from Ostertagia ostertagi excretory-secretory material using proteomics.

Long-term temporal trends in gastrointestinal parasite infection in wild Soay sheep

This study examines 31-year trends in gastrointestinal parasite prevalence and abundance in wild Soay sheep, finding independent effects of host density and year on parasite dynamics.

The development of ovine gastric and intestinal organoids for studying ruminant host-pathogen interactions

This paper develops ovine gastric and intestinal organoids to study host-pathogen interactions in ruminants, showing they maintain tissue-like transcriptomes and can be infected by pathogens.

The right time and place: time- and age-dependent vaccine-enhanced mucosal immunity to parasite infection

This study investigates age-dependent and -independent immune responses to a vaccine against Teladorsagia circumcincta in lambs, showing that younger lambs are more susceptible to infection despite vaccination.

Functionally distinct T-helper cell phenotypes predict resistance to different types of parasites in a wild mammal

The study shows that Th1 and Th2 immune responses predict resistance to different parasites in wild Soay sheep, supporting lab findings in natural settings.

Seasonal dynamics and repeatability of gastrointestinal parasite burdens in wild Soay sheep

This study examines seasonal changes in gastrointestinal parasite burdens in wild Soay sheep, finding differences in seasonality by parasite type and host characteristics.

Prophage-dependent recombination drives genome structural variation and phenotypic heterogeneity in Escherichia coli O157:H7

This paper shows that prophage-dependent recombination generates structural variants in E. coli O157, leading to phenotypic heterogeneity and adaptation.

The influence of liver fluke infection on production in sheep and cattle: a meta-analysis

This study conducts a meta-analysis to quantify the impact of liver fluke infection on livestock performance traits and identifies study design factors influencing results.

Tolerance of liver fluke infection varies between breeds and producers in Scottish beef cattle

This study shows that beef cattle vary in their tolerance to liver fluke infection, with differences observed between breeds and producers.