BiochemistrybioRxiv
Pentamycin biosynthesis in Philippine Streptomyces sp. S816: Cytochrome P450-catalysed installation of the C-14 hydroxyl group
S. Zhou, L. Song, J. Masschelein…·G. L. Challis
The paper identifies Streptomyces sp. S816 as a pentamycin producer and shows that the ptnJ gene encodes a cytochrome P450 responsible for converting filipin III to pentamycin.
DOI 10.1021/acschembio.9b00270