Author

T. Ohkubo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

K. Kunida· 2 shared H. Kimura· 1 shared H. Kinoshita· 1 shared S. Kuroda· 1 shared T. Fujii· 1 shared T. Maekawa· 1 shared Y. Sakumura· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersBioengineering

K. Kunida

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2 papers

Recent·Most cited

On-line reoptimization of mammalian fed-batch culture using a nonlinear model predictive controller

T. Ohkubo, Y. Sakumura, K. Kunida

This study demonstrates the use of a nonlinear model predictive controller (NLMPC) to reoptimize feeding trajectories in mammalian fed-batch cultures, showing improved mAb yield despite process-model mismatch.

bioRxiv · Dec 28, 2022Bioengineering

Development of a microfluidic cell culture and monitoring system for intracellular signaling studies

T. Ohkubo, H. Kinoshita, T. Maekawa, K. Kunida, H. Kimura, S. Kuroda, T. Fujii

The paper develops a microfluidic system to control extracellular signal molecule concentrations and measures intracellular Ca2+ responses in CHO-K1 cells.

bioRxiv · Oct 29, 2018 · PreprintBioengineering