The Novel PII-Interacting Regulator PirC (Sll0944) Identifies 3-Phosphoglycerate Mutase (PGAM) as Central Control Point of Carbon Storage Metabolism in Cyanobacteria
T. Orthwein, J. Scholl, P. Spaet, S. Lucius, M. Koch, B. Macek, M. Hagemann, K. Forchhammer
This study identifies PirC as a PII-interacting regulator that inhibits PGAM, controlling carbon flux towards glycogen or polyhydroxybutyrate in cyanobacteria under nitrogen limitation.
bioRxiv · Sep 11, 2020Microbiology