Small Molecules Restore Azole Activity Against Drug-Tolerant and Drug-Resistant Candida Isolates
P. E. Alabi, C. Gautier, T. P. Murphy, X. Gu, M. Lepaas, V. Aimanianda, J. K. Sello, I. V. Ene
This paper identifies small molecules that restore azole antifungal activity against drug-resistant and drug-tolerant Candida isolates, enhancing fluconazole efficacy and improving host survival in an infection model.
bioRxiv · Mar 31, 2022 · PreprintMicrobiology