Author

I. V. Ene

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:drug response / drug discovery· 4 Assay:proteomics· 4 Organism:C. elegans· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Assay:metagenomics· 2 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. Maufrais· 3 shared C. Gautier· 2 shared R. J. Bennett· 2 shared A. A. Mishra· 1 shared A. Alanio· 1 shared A. C. G. Zimbres· 1 shared A. Dahan· 1 shared A. K. Beach· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersMicrobiology

C. Maufrais

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans.

P. V. Zande, C. Gautier, N. Kawar, C. Maufrais, K. Metzner, E. Wash, A. K. Beach, R. Bracken, E. I. Maciel, C. M. Fernandes, N. V. Solis, M. Del Poeta, S. G. Filler, J. Berman, I. V. Ene, A. Selmecki

This study shows how azole resistance in Candida albicans evolves through copy number variation followed by KSR1 loss of heterozygosity, resulting in a >500-fold resistance increase.

bioRxiv · Mar 5, 2024 · PreprintMicrobiology

Coregulation of extracellular vesicle production and fluconazole susceptibility in Cryptococcus neoformans

J. Rizzo, A. Trottier, F. Moyrand, J.-Y. Coppee, C. Maufrais, A. C. G. Zimbres, T. T. V. Dang, A. Alanio, M. Desnos-Ollivier, I. Mouyna, G. PEHAU-ARNAUDET, P.-H. Commere, S. Novault, I. V. Ene, L. Nimrichter, , G. Janbon

This study identifies regulators of extracellular vesicle production in Cryptococcus neoformans and links EV production to fluconazole resistance.

bioRxiv · Jan 30, 2023 · PreprintMicrobiology

Small Molecules Restore Azole Activity Against Drug-Tolerant and Drug-Resistant Candida Isolates

P. E. Alabi, C. Gautier, T. P. Murphy, X. Gu, M. Lepaas, V. Aimanianda, J. K. Sello, I. V. Ene

This paper identifies small molecules that restore azole antifungal activity against drug-resistant and drug-tolerant Candida isolates, enhancing fluconazole efficacy and improving host survival in an infection model.

bioRxiv · Mar 31, 2022 · PreprintMicrobiology

Candida albicans Isolates 529L and CHN1 Exhibit Stable Colonization of the Murine Gastrointestinal Tract

L. McDonough, A. A. Mishra, N. Tosini, P. Kakade, S. Penumutchu, S.-H. Liang, C. Maufrais, B. Zhai, Y. Taur, P. Belenky, R. J. Bennett, T. J. Hohl, A. Y. Koh, I. V. Ene

This study identifies two Candida albicans isolates that stably colonize the murine gastrointestinal tract, revealing strain-specific differences in colonization and host antimicrobial peptide sensitivity.

bioRxiv · Jun 27, 2021Microbiology

Clearing the FoG: Antifungal tolerance is a subpopulation effect that is distinct from resistance and is associated with persistent candidemia

A. Rosenberg, I. V. Ene, M. Bibi, S. Zakin, E. S. Segal, N. Ziv, A. Dahan, A. L. Colombo, R. J. Bennett, J. G. Berman

This study defines antifungal tolerance as a subpopulation effect distinct from resistance, showing it correlates with persistent candidemia and can be reduced by adjuvant drugs.

bioRxiv · Mar 2, 2018Microbiology