Surviving hypothermia by ferritin-mediated iron detoxification
T. Pekec, J. Lewandowski, A. A. Komur, D. Sobanska, Y. Guo, K. Switonska-Kurkowska, M. Frankowski, M. Figiel, R. Ciosk
The paper identifies a conserved mechanism involving ferritin proteins that enhances cold survival in nematodes and mammalian neurons by detoxifying iron-related reactive oxygen species.
bioRxiv · Jan 30, 2021Physiology