Author

T. R. Young

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:database / resource· 1

Frequent Co-Authors

N. J. Robinson· 3 shared D. Osman· 2 shared S. E. Clough· 2 shared A. R. Clarke· 1 shared A. W. Foster· 1 shared B. A. Kerr· 1 shared B. M. Foster· 1 shared D. Zaidi· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersBiochemistry

N. J. Robinson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Hyperaerated metalation calculator for E. coli strain JM109 (DE3) grown in LB media

S. E. Clough, D. Osman, T. R. Young, N. J. Robinson

The paper archives data supporting a new calculator for predicting metal occupancies in hyperaerated E. coli cells grown in LB media.

bioRxiv · Sep 2, 2022 · PreprintBiochemistry

Metalation calculators for E. coli strain JM109 (DE3): Aerobic, anaerobic and hydrogen peroxide exposed cells cultured in LB media

N. J. Robinson, A. W. Foster, S. E. Clough, T. R. Young, A. R. Clarke, Z. Aki

The paper develops web-based calculators and spreadsheets to predict metal occupancies in E. coli cells under different growth conditions using metal-affinity data and gene expression measurements.

bioRxiv · May 6, 2022Cell Biology

Calculating metalation in cells reveals CobW acquires CoII for vitamin B12 biosynthesis upon binding nucleotide

T. R. Young, M. A. Martini, D. Osman, R. J. Morton, E. Deery, M. J. Warren, N. J. Robinson

The paper develops a metalation-calculator to determine metal occupancy in proteins, revealing CobW acquires CoII for vitamin B12 biosynthesis upon binding nucleotide and MgII.

bioRxiv · Jun 26, 2020Biochemistry

CD117/c-kit in Cancer Stem Cell-Mediated Progression and Therapeutic Resistance

B. M. Foster, D. Zaidi, T. R. Young, M. E. Mobley, B. A. Kerr

This study investigates the role of CD117/c-kit in cancer stem cell-mediated progression and therapeutic resistance through its signaling axis with stem cell factor.

bioRxiv · Feb 11, 2018Cancer Biology