Spatio-temporal transcriptomic analysis reveals distinct nephrotoxicity, DNA damage and regeneration response after cisplatin
L. S. Wijaya, S. Kunnen, P. Trairatphisan, C. Fisher, M. Crosby, K. Schaefer, K. Bodie, E. Vaughan, L. Breidenbach, T. Reich, D. Clausznitzer, S. A. Bonnet, S. Zheng, C. Pont, J. L. Stevens, , B. v. d. Water
This study uses spatial transcriptomics to analyze cisplatin-induced nephrotoxicity and regeneration in different kidney segments, identifying distinct molecular responses and biomarkers.
bioRxiv · Jan 3, 2023Pharmacology & Toxicology