Author

L. Breidenbach

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

B. v. d. Water· 1 shared C. Fisher· 1 shared C. Pont· 1 shared D. Clausznitzer· 1 shared E. D. Pratt· 1 shared E. Vaughan· 1 shared H. Peterson· 1 shared J. F. Blankenhorn· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

B. v. d. Water

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2 papers

Recent·Most cited

Spatio-temporal transcriptomic analysis reveals distinct nephrotoxicity, DNA damage and regeneration response after cisplatin

L. S. Wijaya, S. Kunnen, P. Trairatphisan, C. Fisher, M. Crosby, K. Schaefer, K. Bodie, E. Vaughan, L. Breidenbach, T. Reich, D. Clausznitzer, S. A. Bonnet, S. Zheng, C. Pont, J. L. Stevens, , B. v. d. Water

This study uses spatial transcriptomics to analyze cisplatin-induced nephrotoxicity and regeneration in different kidney segments, identifying distinct molecular responses and biomarkers.

bioRxiv · Jan 3, 2023Pharmacology & Toxicology

Novel Bruton's Tyrosine Kinase (BTK) substrates for time-resolved luminescence assays

N. Widstrom, M. Perez, E. D. Pratt, J. L. Heier, J. F. Blankenhorn, L. Breidenbach, H. Peterson, L. L. Parker

The paper identifies novel BTK substrates and develops a pipeline to generate synthetic substrates for time-resolved luminescence assays.

bioRxiv · Apr 5, 2022Biochemistry