Author

T. Sagmeister

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

T. Pavkov-Keller· 3 shared I. Uson· 2 shared A. Castellvi· 1 shared A. Medina· 1 shared B. D. Geronimo· 1 shared C. Buhlheller· 1 shared C. F. Rodriguez Gamez· 1 shared F. Govantes· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiochemistry

T. Pavkov-Keller

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Unmasking Crucial Residues in Adipose Triglyceride Lipase (ATGL) for Co-Activation with Comparative Gene Identification-58 (CGI-58)

N. Kulminskaya, C. F. Rodriguez Gamez, P. Hofer, I. K. Cerk, N. Dubey, R. Viertlmayr, T. Sagmeister, T. Pavkov-Keller, R. Zechner, M. Oberer

This study identifies key residues in ATGL critical for co-activation with CGI-58 using mutagenesis and AlphaFold modeling.

bioRxiv · Jun 26, 2023Biochemistry

Vibrio cholerae's ToxRS Bile Sensing System

N. Gubensaek, T. Sagmeister, C. Buhlheller, B. D. Geronimo, G. E. Wagner, L. Petrowitsch, M. A. Graewert, M. Rotzinger, T. I. Berger, J. Schäfer, I. Uson, J. Reidl, P. A. Sanchez-Murcia, K. Zangger, T. Pavkov-Keller

This study reveals the crystal structure of ToxRS and its interaction with bile acids, showing ToxS's folded bile-binding pocket depends on ToxR and highlighting its conservation across Vibrio species.

bioRxiv · May 2, 2023Biochemistry

Exploring generality of experimental conformational changes with AlphaFold predictions

A. Castellvi, A. Medina, G. Petrillo, T. Sagmeister, T. Pavkov-Keller, F. Govantes, K. Diederichs, M. D. Sammito, I. Uson

The paper uses AlphaFold predictions to explore conformational changes in LysR-type transcriptional regulators by comparing experimental structures with predicted models.

bioRxiv · Apr 12, 2022 · PreprintBiophysics