Limited inhibition of multiple nodes in a driver network blocks metastasis
A. E. Yesilkanal, D. Yang, P. Tiwari, A. U. Sabino, J. Lee, X.-H. Xie, S. Sun, C. Dann, E. Steinberg, T. Stuhlmiller, C. Frankenberger, E. Goldsmith, G. L. Johnson, A. F. Ramos, M. R. Rosner
The paper shows that limited inhibition of multiple core pathways in a driver network effectively blocks metastasis in mouse breast cancer models.
bioRxiv · Jun 5, 2020Cancer Biology