Author

M. R. Rosner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

C. Dann· 4 shared D. Yang· 4 shared A. Mohamed· 2 shared A. Valdespino· 2 shared D. Silva· 2 shared G. Randall· 2 shared H. Gula· 2 shared L. C. Nguyen· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

C. Dann

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Analysis of gene expression heterogeneity reveals therapeutic targets and novel regulators of metastasis

D. Yang, C. Dann, A. Valdespino, L. Robinson-Mailman, M. Henn, M. Chen, G. Balazsi, M. R. Rosner

The paper identifies therapeutic targets and novel metastasis regulators by analyzing gene expression heterogeneity in triple-negative breast cancer using single-cell RNA sequencing.

bioRxiv · Dec 16, 2022 · PreprintCancer Biology

Volumetric microscopy of CD9 and CD63 reveals distinct subpopulations and novel structures of extracellular vesicle in situ in triple negative breast cancer cells

E. D. White, N. D. Walker, H. Yi, A. R. Dinner, N. F. Scherer, M. R. Rosner

bioRxiv · Nov 8, 2022 · PreprintBiophysics

SARS-CoV-2 diverges from other betacoronaviruses in only partially activating the IRE1α/XBP1 ER stress pathway in human lung-derived cells

L. C. Nguyen, D. M. Renner, D. Silva, D. Yang, N. Parenti, K. M. Medina, V. Nicolaescu, H. Gula, N. Drayman, A. Valdespino, A. Mohamed, C. Dann, K. Wannemo, L. Robinson-Mailman, A. Gonzalez, , S. R. Weiss

This study compares how SARS-CoV-2 and other betacoronaviruses activate the IRE1α/XBP1 ER stress pathway in human lung cells, finding that SARS-CoV-2 only partially activates it, potentially evading host immune detection.

bioRxiv · Dec 30, 2021 · PreprintMicrobiology

Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response

L. C. Nguyen, D. Yang, V. Nicolaescu, T. Best, S. Chen, J. B. Friesen, N. Drayman, A. Mohamed, C. Dann, D. Silva, H. Gula, K. A. Jones, J. M. Millis, B. C. Dickinson, S. Tay, , M. R. Rosner

This study shows that cannabidiol inhibits SARS-CoV-2 replication and enhances the host innate immune response in lung cells and human patients.

bioRxiv · Mar 10, 2021 · PreprintMicrobiology

Limited inhibition of multiple nodes in a driver network blocks metastasis

A. E. Yesilkanal, D. Yang, P. Tiwari, A. U. Sabino, J. Lee, X.-H. Xie, S. Sun, C. Dann, E. Steinberg, T. Stuhlmiller, C. Frankenberger, E. Goldsmith, G. L. Johnson, A. F. Ramos, M. R. Rosner

The paper shows that limited inhibition of multiple core pathways in a driver network effectively blocks metastasis in mouse breast cancer models.

bioRxiv · Jun 5, 2020Cancer Biology

Metabolically activated macrophages in mammary adipose tissue link obesity to triple-negative breast cancer

P. Tiwari, A. Blank, C. Cui, K. Schoenfelt, G. Zhou, Y. Xu, A. Shah, S. Khan, M. R. Rosner, L. Becker

This study shows that obesity-induced metabolically activated macrophages in mammary adipose tissue promote triple-negative breast cancer stemness and tumorigenesis through GP130 signaling.

bioRxiv · Jul 17, 2018Cancer Biology