Author

T. Suormala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

D. S. Froese· 2 shared S. Lutz· 2 shared A. Chaikuad· 1 shared A. Oberholzer· 1 shared B. Fowler· 1 shared C. Buerer· 1 shared E. Krysztofinska· 1 shared E. Rembeza· 1 shared

Activity by Year

2018-2018 · peak 2/yr

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10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

D. S. Froese

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2 papers

Recent·Most cited

Genetic, structural, and functional analysis of mutations causing methylmalonyl-CoA epimerase deficiency

K. Heuberger, H. J. Bailey, P. Burda, A. Chaikuad, E. Krysztofinska, T. Suormala, C. Buerer, S. Lutz, B. Fowler, D. S. Froese, W. W. Yue, M. R. Baumgartner

The paper identifies ten new patients with MCEE deficiency, analyzes mutations in the MCEE gene, and reveals structural and functional defects in the enzyme caused by these mutations.

bioRxiv · Nov 30, 2018Biochemistry

Structural basis of human 5,10-methylenetetrahydrofolate reductase (MTHFR) regulation by phosphorylation and S-adenosylmethionine inhibition

D. S. Froese, J. Kopec, E. Rembeza, G. A. Bezerra, A. Oberholzer, T. Suormala, S. Lutz, R. Chalk, O. Borkowska, M. Baumgartner, W. Yue

This study presents the 2.5 Å resolution crystal structure of human MTHFR, revealing its architecture and how phosphorylation and SAM binding regulate its activity.

bioRxiv · Feb 26, 2018Biochemistry