Author

T. T. Chandrasekaran

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T. T. ChandrasekaraniD1 paper · University of Stuttgart

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Albert JeltschiD· 1 shared Alexander Bröhm· 1 shared Alexandra G. Kouroukli· 1 shared Michel ChoudalakisiD· 1 shared Ole AmmerpohliD· 1 shared Pavel BashtrykoviD· 1 shared Philipp RathertiD· 1 shared Sara Weirich· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Albert JeltschORCID

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1 paper

Recent·Most cited

SETDB1 activity is globally directed by H3K14 acetylation via its Triple Tudor Domain

T. T. Chandrasekaran, Michel Choudalakis, Alexander Bröhm, Sara Weirich, Alexandra G. Kouroukli, Ole Ammerpohl, Philipp Rathert, Pavel Bashtrykov, Albert Jeltsch

This study shows that H3K14 acetylation directs SETDB1 activity via its Triple Tudor Domain, enabling H3K9 methylation and heterochromatin formation.

Nucleic Acids Research · Oct 24, 2024Peer-reviewedBiochemistry