Author

Philipp Rathert

University of StuttgartORCID 0000-0003-1477-136XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Jannis StadageriD· 2 shared Albert JeltschiD· 1 shared Alexander Bröhm· 1 shared Alexandra G. Kouroukli· 1 shared Andrew G. ClarkiD· 1 shared Angelika HaußeriD· 1 shared Chiara BernardiniiD· 1 shared Dilan Torcuk· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

Jannis StadagerORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintJun 10, 2026

Interplay between β-catenin transcriptional and cell-cell junction activity regulates homeostasis and collective dynamics in the intestinal epithelium

Thao Nguyen, Sarbari Saha, Fabian Gärtner…·Andrew G. Clark

This study investigates how β-catenin's dual roles in Wnt signaling and cell-cell junctions affect intestinal epithelial homeostasis and collective dynamics.

DOI 10.64898/2026.06.10.731321

mouseATAC-seq

𝕏 PostBluesky

BiochemistryCell Reports MethodsPeer-reviewedJun 1, 2025

CRISPR gene and transcriptome engineering (CRISPRgate) improves loss-of-function genetic screening approaches

Jannis Stadager, Chiara Bernardini, Laura Hartmann…·Philipp Rathert

CRISPRgate improves loss-of-function screening by combining CRISPRko and CRISPRi to enhance gene repression and reduce noise in genetic studies.

5 citations

humanCRISPR screen

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BiochemistryNucleic Acids ResearchPeer-reviewedOct 24, 2024

SETDB1 activity is globally directed by H3K14 acetylation via its Triple Tudor Domain

T. T. Chandrasekaran, Michel Choudalakis, Alexander Bröhm…·Albert Jeltsch

This study shows that H3K14 acetylation directs SETDB1 activity via its Triple Tudor Domain, enabling H3K9 methylation and heterochromatin formation.

8 citations

humanChIP-seq

𝕏 PostBluesky