T. Winkler

Inactivation of p53 drives breast cancer brain metastasis by altering fatty acid metabolism

This study shows that p53 inactivation promotes breast cancer brain metastasis by altering fatty acid metabolism, with implications for therapeutic targeting.

Regional pulmonary perfusion, blood volume, and their relationship change during early ARDS in an experimental study

This study examines how regional pulmonary perfusion and blood volume change in early ARDS using PET imaging in sheep, finding a shift from linear to curvilinear relationship between the two.

Modulation of Polar Auxin Transport Identifies the Molecular Determinants of Source-Sink Carbon Relationships and Sink Strength in Poplar

This study uses auxin modulators to investigate carbon allocation and sink strength in poplar, identifying molecular factors like polygalacturonase and β-amylase that influence sink activity.

Elevated expression of ACE2 in tumor-adjacent normal tissues of cancer patients

The paper finds elevated ACE2 expression in tumor-adjacent normal tissues of cancer patients, suggesting increased COVID-19 risk may extend beyond those with immune suppression.

Chemical biofilm dislodgement with chelating and reducing agents in comparison to sonication: implications for the diagnosis of implant associated infection

This study compares sonication and chemical agents (EDTA, DTT) for biofilm dislodgement, finding sonication more effective for microbial detection in implant-associated infections.