Repurposing beta3-adrenergic receptor agonists for Alzheimer's disease: Beneficial effects on recognition memory and amyloid pathology in a mouse model.
M. Tournissac, T.-M. Vu, N. Vrabic, C. Hozer, C. Tremblay, K. Melancon, E. Planel, F. Pifferi, F. Calon
This study shows that β3AR agonists improve recognition memory and reduce insoluble Aβ42/Aβ40 ratio in 3xTg-AD mice.
bioRxiv · May 25, 2020Pharmacology & Toxicology