Author

Takehide Sakamoto

Kyoto University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Daisuke Yarimizu· 1 shared Emi HasegawaiD· 1 shared Hikari Uehara· 1 shared Masao DoiiD· 1 shared Tom MacphersoniD· 1 shared Xinyan Shao· 1 shared Yuki HamadaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperPathology

Daisuke Yarimizu

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1 paper

Recent·Most cited

NAD boosting by CD38 inhibition drives reversal of a pathological vicious cycle of intracrine activity and inflammation in eyelid meibomian gland involution

Yuki Hamada, Takehide Sakamoto, Daisuke Yarimizu, Hikari Uehara, Xinyan Shao, Tom Macpherson, Emi Hasegawa, Masao Doi

This study shows that inhibiting CD38 boosts NAD levels, reversing a harmful cycle of inflammation and reduced intracrine activity in aged meibomian glands.

bioRxiv · Nov 1, 2026 · PreprintPathology