Author

Xinyan Shao

Kyoto University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:Ribo-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Emi HasegawaiD· 3 shared Masao DoiiD· 3 shared Tom MacphersoniD· 3 shared Youichi Tanaka· 2 shared Aoi Harui· 1 shared Chenyang Xiao· 1 shared Daisuke OnoiD· 1 shared Daisuke Yarimizu· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersNeuroscience

Emi HasegawaORCID

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3 papers

Recent·Most cited

NAD boosting by CD38 inhibition drives reversal of a pathological vicious cycle of intracrine activity and inflammation in eyelid meibomian gland involution

Yuki Hamada, Takehide Sakamoto, Daisuke Yarimizu, Hikari Uehara, Xinyan Shao, Tom Macpherson, Emi Hasegawa, Masao Doi

This study shows that inhibiting CD38 boosts NAD levels, reversing a harmful cycle of inflammation and reduced intracrine activity in aged meibomian glands.

bioRxiv · Nov 1, 2026 · PreprintPathology

The slow-acting G-protein Gz defines the duration of circadian rest time

Youichi Tanaka, Yuto Fujita, Tom Macpherson, Aoi Harui, Sumihiro Kunisue, Genzui Setsu, Xinyan Shao, Daisuke Ono, Takatoshi Hikida, Yoshihisa Fujita, Michiyuki Matsuda, Hitoshi Okamura, Emi Hasegawa, Masao Doi

This study shows that Gz G-protein regulates the duration of circadian rest time by modulating cAMP-PKA activity and transcriptome remodeling in the SCN.

bioRxiv · May 27, 2026 · PreprintNeuroscience

Translational regulation of GAD1 identified by circadian and light-responsive ribosome-bound transcriptome analysis in the mouse hypothalamic suprachiasmatic nucleus

Xinyan Shao, Sui-Wen Hsiao, Chenyang Xiao, Huihua Zhou, Youichi Tanaka, Tom Macpherson, Yuichi Shichino, Shintaro Iwasaki, Emi Hasegawa, Masao Doi

The paper identifies translational regulation of GAD1 in the mouse SCN using Ribo-seq and RNA-seq, showing light-induced ribosome binding without mRNA changes.

bioRxiv · Jan 27, 2026 · PreprintNeuroscience