Masao Doi

This study shows that inhibiting CD38 boosts NAD levels, reversing a harmful cycle of inflammation and reduced intracrine activity in aged meibomian glands.

The paper introduces GT-SPARCL, a genetic method for low-density neuronal labeling in mice, and applies it to reveal morphological subtypes of AVP neurons in the SCN.

This study shows that Gz G-protein regulates the duration of circadian rest time by modulating cAMP-PKA activity and transcriptome remodeling in the SCN.

The paper identifies translational regulation of GAD1 in the mouse SCN using Ribo-seq and RNA-seq, showing light-induced ribosome binding without mRNA changes.

This paper introduces methods to absolute quantify ribosome flux on transcripts, revealing ribosome allocation under stress, aging, and across cell types.