Programmable mammalian translational modulators by CRISPR-associated proteins
Shunsuke Kawasaki, Hiroki Ono, Moe Hirosawa, Takeru Kuwabara, Shunsuke Sumi, Suji Lee, Knut Woltjen, Hirohide Saito
This paper develops CaRTRIDGE, a system using CRISPR-associated proteins to control mRNA translation, creating orthogonal switches and synthetic circuits in mammalian cells.
Nature Communications · Apr 19, 2023Peer-reviewedSynthetic Biology