Author

Moe Hirosawa

Kyoto University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Hirohide SaitoiD· 2 shared Hiroki OnoiD· 2 shared Belinda Kaswandy· 1 shared Karin Hayashi· 1 shared Knut WoltjeniD· 1 shared Mai UedaiD· 1 shared Maya Lopez· 1 shared Shunsuke KawasakiiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersDevelopmental Biology

Hirohide SaitoORCID

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2 papers

Recent·Most cited

Transient let-7/miR-98 reprograms primed pluripotency to induce naivehuman PSCs

Yoshihiko Fujita, Moe Hirosawa, Karin Hayashi, Hiroki Ono, Belinda Kaswandy, Mai Ueda, Maya Lopez, Takuya Yamamoto, Yasuhiro Takashima, Hirohide Saito

This paper identifies miR-98-5p as a let-7 family microRNA that enhances naive human PSC induction by repressing NR6A1 and activating BMP2/4 signaling, improving resetting efficiency to ~80%.

bioRxiv · Oct 14, 2025 · PreprintDevelopmental Biology

Programmable mammalian translational modulators by CRISPR-associated proteins

Shunsuke Kawasaki, Hiroki Ono, Moe Hirosawa, Takeru Kuwabara, Shunsuke Sumi, Suji Lee, Knut Woltjen, Hirohide Saito

This paper develops CaRTRIDGE, a system using CRISPR-associated proteins to control mRNA translation, creating orthogonal switches and synthetic circuits in mammalian cells.

Nature Communications · Apr 19, 2023Peer-reviewedSynthetic Biology