Single-nucleus RNA/ATAC-seq Reveals SWI/SNF complex activation and allele-specific non-myocyte activation in HCM mouse models
Tilo Thottakara, Arun Padmanabhan, Talha Tanriverdi, Tharika Thambidurai, Jose A Diaz-Rg, Sanika Amonkar, Jeffrey E. Olgin, Carlin S. Long, Maria Roselle Abraham
The paper uses single-nucleus RNA/ATAC-seq to analyze HCM mouse models and identifies differences in gene expression and signaling pathways between mutant and wild-type hearts.
bioRxiv · Apr 24, 2024 · PreprintBioinformatics