Tharika Thambidurai

This study investigates systemic metabolic changes in a mouse model of left ventricular hypertrophy, finding that exogenous long-chain fatty acid supplementation improves mitochondrial function but does not fully reverse the disease phenotype.

This study shows that dietary elderberry extract, through gut microbial conversion to hydrocinnamic acid, improves obesity-related metabolic disorders in mice by enhancing insulin sensitivity and reducing liver fat.

The paper uses single-nucleus RNA/ATAC-seq to analyze HCM mouse models and identifies differences in gene expression and signaling pathways between mutant and wild-type hearts.